GC-MS

GC-MS: A laboratory technique used to identify and quantify compounds in cannabis through gas chromatography and mass spectrometry.

Also called / Category:

Gas Chromatography-Mass Spectrometry / Lab Testing & QA/QC

Key takeaways:

• GC-MS is essential for cannabis quality control.
• It helps in detecting both the type and amount of cannabinoids and offset-4 transition-colors hover:underline" title="Learn more about Terpenes">terpenes.
• Commonly used in regulatory compliance testing.
• Provides precise and reliable results.

What it is / How it shows up:

GC-MS, or Gas Chromatography-Mass Spectrometry, is a method frequently mentioned in Certificates of Analysis provided by cannabis labs. This technique separates chemical compounds in a sample and identifies them through their mass spectral signature. It is integral in verifying the potency and purity of cannabis products by analyzing cannabinoids, terpenes, and potential contaminants. Consumers may encounter GC-MS results when they examine product lab results to ensure safety and quality.

How it’s measured or identified:

• Sample preparation and injection into the GC unit.
• Separation of compounds via gas chromatography.
• Detection and identification via mass spectrometry.
• Quantification through comparison with known standards.

Use in context:

• "The GC-MS results show high levels of THC in this strain."
• "GC-MS analysis confirmed the absence of pesticides in the sample."
• "We rely on GC-MS for accurate terpene profiling."

Safety & compliance in Canada:

• GC-MS ensures compliance with Health Canada's cannabis regulations.
• Used to verify the absence of harmful chemicals.
• Mandatory for licensed producers to guarantee product safety.

Related terms / See also:

• 11-Hydroxy-THC
• Acidic cannabinoids
• Aflatoxins/ochratoxin
• Anandamide (AEA)
• Aroma profile
• Batch/lot

FAQs:

Q: Why is GC-MS used in cannabis testing?

A: GC-MS is used for its accuracy and ability to identify and quantify various compounds, ensuring cannabis products meet safety and quality standards.

Q: Can GC-MS detect all cannabinoids?

A: GC-MS is excellent for detecting many cannabinoids, but it may require derivatization for those that are thermally labile, like acidic cannabinoids.

Sources:

• Health Canada
• PubChem