LC-MS/MS is an analytical technique used to identify and quantify compounds in cannabis products.
Also called / Category:
Liquid Chromatography-Mass Spectrometry / Lab Testing & QA/QC
Key takeaways:
- Highly accurate method for detecting cannabinoids and contaminants.
- Commonly used in cannabis testing labs for quality assurance.
- Helps ensure consumer safety by identifying harmful substances.
What it is / How it shows up:
LC-MS/MS is often found on Certificates of Analysis for cannabis products, providing detailed information about the concentration of cannabinoids, offset-4 transition-colors hover:underline" title="Learn more about Terpenes">terpenes, and potential contaminants like pesticides or heavy metals. This technique combines liquid chromatography, which separates mixtures, with mass spectrometry, which identifies and quantifies the individual components. It's a critical method in the cannabis industry for ensuring product safety and consistency, helping to maintain regulatory compliance and consumer trust. With its high sensitivity and specificity, LC-MS/MS is a preferred choice for comprehensive cannabis testing.
How it’s measured or identified:
- Uses tandem mass spectrometry for precise measurement.
- Quantifies compounds in parts per million (ppm) or billion (ppb).
- Requires sophisticated lab equipment and trained technicians.
Use in context:
- Determines THC and CBD levels in cannabis extracts.
- Identifies residual solvents in cannabis concentrates.
- Detects aflatoxins and other contaminants in edible products.
Safety & compliance in Canada:
- Ensures products meet Health Canada safety standards.
- Mandatory for licensed cannabis producers to ensure quality control.
Related terms / See also:
FAQs:
What is the main use of LC-MS/MS in cannabis? LC-MS/MS is primarily used to test for cannabinoid potency and detect contaminants, ensuring the safety and quality of cannabis products.
Is LC-MS/MS testing mandatory for cannabis products in Canada? Yes, licensed producers in Canada must use LC-MS/MS to ensure their products comply with Health Canada regulations.
Sources:
- Health Canada
- PubChem